CRISTALLOIDI E COLLOIDI PDF

The Colloid Crystalloid Question • Is one of the oldest. • Basic yet fundamental question. • The first intervention given. • To every patient. • Often several litres. A volume expander is a type of intravenous therapy that has the function of providing volume There are two main types of volume expanders: crystalloids and colloids. Crystalloids are aqueous solutions of mineral salts or other water- soluble. Colloids and crystalloids are types of fluids that are used for fluid replacement, often intravenously (via a tube straight into the blood).

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The choice of fluids may also depend on the chemical properties of the medications being given. Participants had traumaburns, or medical conditions such as sepsis. Goal-directed fluid therapy is cristallodii with either crystalloid or HES. We found moderate-certainty evidence that there is probably little or no difference between using starches or crystalloids in mortality at: No difference in the incidence of postoperative complications was seen between the groups.

Crystalloid or colloid for goal-directed fluid therapy in colorectal surgery.

We are uncertain whether they are better than crystalloids at reducing death, need for blood transfusion or need for renal replacement therapy filtering the blood, with or without dialysis machines, if kidneys fail when given to critically ill people who need fluid cristalloido.

Colloids versus crystalloids for fluid resuscitation in critically ill patients.

We are uncertain whether using dextrans, albumin or FFP, or crystalloids affects the need for blood transfusion. It may be vristalloidi for fluid replacement. Since the lost blood was replaced with a suitable fluid, the now diluted blood flows more easily, even crisatlloidi the small vessels. We noted risk of selection bias in some studies, and, as most studies were not prospectively registered, risk of selective outcome reporting.

For the most updated list of ABA Keywords and definitions go to https: Cochrane Database Syst Rev. Gelatins versus crystalloids We found low-certainty evidence that there cgistalloidi be little or no difference between gelatins or crystalloids in mortality: Critically ill people may lose fluid because of serious conditions, infections e.

Similarly, evidence for adverse events is uncertain. Similarly, we are uncertain if colloids or crystalloids increase the number of adverse events. Certainty of the evidence Some study authors did not report study methods clearly and many did not register their studies before they started, so we could not be certain whether the study outcomes were decided before or after they saw the results.

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We found moderate-certainty evidence that using starches for fluid replacement probably slightly increases the need for renal replacement therapy.

Conclusions Using colloids starches; dextrans; or albumin or FFP compared to crystalloids for fluid replacement probably makes little or no difference to the number of critically ill people who die. The primary outcome measure was the incidence of gastrointestinal GI morbidity on postoperative day 5.

A patient at rest uses only 25 percent of the oxygen available in their blood. Key results We found moderate-certainty evidence that using colloids starches; dextrans; or albumin or FFP compared to crystalloids for fluid replacement probably makes little or no difference to the number of critically ill people who die within 30 or 90 days, or by the end of study follow-up.

Secondary outcome cristalloivi included the incidence of postoperative complications, hospital length of stay, and the effect of trial fluids on coagulation and inflammation. Using starches, dextrans, albumin or FFP moderate-certainty evidenceor gelatins low-certainty evidenceversus crystalloids probably makes little or no difference to mortality. This is roughly 4 times more concentrated than medical “normal saline” of 0.

To assess the effect of using colloids versus crystalloids in critically ill people requiring fluid volume replacement on mortalityneed for blood transfusion or renal replacement therapy RRTand adverse events specifically: This way remaining red blood cells can still oxygenate body tissue. One study comparing gelatins did not report results for renal replacement therapy according to the type of fluid given, and no studies comparing dextrans assessed renal replacement therapy. We found moderate-certainty evidence that there is probably little or no difference between using dextrans or crystalloids in mortality at: We are uncertain whether either fluid type reduces need for blood transfusion RR 1.

In these situations, the only alternatives are blood transfusions, packed red blood cplloidi, or oxygen therapeutics if available.

Crystalloid vs colloid rx

There are many clinical factors that may affect the decision to use a crystalloid versus colloid fluid. Crystalloids and colloids are the primary options for intravenous fluid resuscitation. We are uncertain whether dextrans or crystalloids reduce the need for blood transfusion, as we found little or no difference in blood transfusions RR 0.

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NS is used frequently in intravenous drips IVs for patients who cannot take fluids orally and have developed or are in danger of developing dehydration or hypovolemia. We also searched clinical trials registers. We included randomised controlled trials RCTs and quasi- RCTs of critically ill people who required fluid volume replacement in hospital or emergency out-of-hospital settings. Study characteristics The evidence is current to February There are two main types of volume expanders: Normal saline NS is the commonly used term for a solution of 0.

It is an intravenous colloid that behaves much like blood filled with albumins. Starches versus crystalloids We found moderate-certainty evidence that there is probably little or no difference between using starches or crystalloids in mortality at: Critically ill people may lose large amounts of blood because of trauma or burnsor have serious conditions or infections e. The heart pumps more blood with each beat. However, we are uncertain whether using other types of colloids, compared to crystalloids, makes a difference to whether people need a blood transfusion because the certainty of the evidence is very low.

Crystalloid or colloid for goal-directed fluid therapy in colorectal surgery.

We found little or no difference in allergic reactions for the use of dextrans four studiesgelatins one studyand albumin or FFP one study. Colloid or crystalloid solutions may be used for this purpose.

Participants had a range of conditions typical of critical illness. Recent work has demonstrated that new generations of HES have a good safety profile, but their routine use in the perioperative setting has not been demonstrated to confer outcome benefit.

Colloids or crystalloids for fluid replacement in critically people

We found low-certainty evidence that there may be little or no difference between gelatins or crystalloids in mortality: This could lead to increased gastrointestinal wall edema, which may slow post-operative gastrointestinal recovery. Colloids d larger insoluble molecules, such as gelatin ; blood itself is a colloid.

Crystalloids are aqueous solutions of mineral salts or other water-soluble molecules. Physiological dissociation is approximately 1. We found moderate-certainty evidence that there is probably little or no difference between using albumin or FFP or using crystalloids in mortality at: