Retrieved sources were further explored applying both the snowball approach Table 1. Cystatin C (CysC) reference values as reported in literature in full term. A cistatina C tem sido proposta com um marcador alternativo da filtração em relação à creatinina. O presente estudo foi conduzido com o objetivo de avaliar o . Request PDF on ResearchGate | La cistatina C aporta más información que otros parámetros de función renal en la estratificación del riesgo.

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All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Subscribe to our Newsletter. Progressive decline in renal function in diabetic patients with and without albuminuria. Diagnostic efficiency of cystatin C and creatinine as markers of reduced glomerular filtration rate in the elderly.

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Thyroid function differently affects serum cystatin C and creatinine concentrations. Continuing navigation will be considered as acceptance of this use.


How to estimate GFR-serum creatinine, serum cystatin C or equations? Novel methods are needed for early and accurate detection of DN.

Clin Chem ; Diabetic nephropathy DN is the leading cause of chronic kidney disease. Icstatina C identifies chronic kidney disease patients at higher risk for complications.

It is known that the serum cystatin C level increases with advancing age. This is an open-access article distributed under the terms of the Creative Commons Attribution License. However, these measurements are not sufficient in early diagnosis and monitoring the progression of DN.


Serum cystatin C: a practical alternative for renal function evaluation?

Serum creatinine concentration is an imperfect measure of GFR. Following thorough medical history and detailed physical examination, blood samples were taken from all participants for measurement of fasting blood glucose, HbA1c, blood urea, creatinine and electrolytes, lipid profile, serum albumin, high sensitive C reactive protein hsCRP.

Continuing navigation will be considered as acceptance of this use.

Although serum cystatin C determination is increasingly being used in clinical practice worldwide, its limitations as well as the conditions its use is in fact indicated are not adequately established; on the other hand serum creatinine and creatinine clearance is an easily available and low cost laboratory marker with well-known limitations that can be used routinely in the assessment of renal function.

Vantagens e desvantagens desse marcador foram aqui discutidas. We think that this situation might be due to the limited number of cases in the patient group.

Differential estimation of CKD using creatinine- versus cystatin C-based estimating equations by category of body mass index. Glomerular filtration rate estimated by cystatin C among different clinical presentations.

Stable production rate by nucleated cells, free filtration by renal glomeruli due to low molecular weight and a positive charge of the protein, and independence on age, sex, race and lean muscle mass render serum concentration of cysC an acknowledged marker of renal failure and mild renal dysfunction in clinical practice.

This patient group was the sole patient group with Cistatinz.


Cystatin C in acute kidney injury. A comparison between cystatic C, plasma creatinine and the Cockcroft and Gault for the estimation of glomerular filtration rate. An improved estimator of glomerular filtration rate? A marker of renal function or something more? Show all Show less.


Is cystatin C a marker of glomerular filtration rate in thyroid dysfunction? Measurement of cystatin C and creatinine in urine. Are you a health professional able to prescribe or dispense drugs? We compared five formulas: Nephrol Dial Transplant ; Interest of cystatin C in screening diabetic patients for early impairment of renal function.

Si continua navegando, consideramos que acepta su uso. Cystatin C was potentially superior to creatinine and in this study and cystatin C seems to detect changes in glomerular filtration rate earlier than creatinine and may be a better screening method for chronic kidney disease in systemic lupus erythematosus. CiteScore measures average citations received per document published.

Cystatin C reference values and aging. J Am Coll Cardiol ; This was a cross-sectional study which was conducted at the Department of Endocrinology in Baskent University School of Medicine, Istanbul, Turkey, duringwho agreed to participate in the study. Show all Show less.

The laboratory parameters of the groups are shown in Table 1. Serum cystatin C is superior to serum creatinine as a marker of kidney function: Patients with type 2 diabetes mellitus without known overt diabetic nephropathy were included in the study.

As pursuant to our study, two studies show that cystatin C is not more sensitive than creatinine.